| Thursday, November 30th, 1961 |
| Drafted 3B Bob Bailey in the 1961 first-year player draft (Round 1, Pick 8, 8th overall pick). |
| Drafted MR Paul Toth in the 1961 first-year player draft (Round 2, Pick 8, 32nd overall pick). |
| Drafted MR Jack Cullen in the 1961 first-year player draft (Round 3, Pick 9, 55th overall pick). |
| Drafted MR Bob Priddy in the 1961 first-year player draft (Round 4, Pick 10, 79th overall pick). |
| Drafted 3B Frank Kostro in the 1961 first-year player draft (Round 5, Pick 13, 107th overall pick). |
| Sunday, November 12th, 1961 |
| CL Tom Acker becomes a free-agent. |
| RF Paul Smith becomes a free-agent. |
| SP Phil Regan received a 1-year contract through automatic renewal worth a total of $14,763. |
| SS Jim Mahoney received a 1-year contract through automatic renewal worth a total of $14,763. |
| CL Ron Piche received a 1-year contract through automatic renewal worth a total of $14,763. |
| 2B Bob Saverine received a 1-year contract through automatic renewal worth a total of $14,763. |
| MR Al Neiger received a 1-year contract through automatic renewal worth a total of $14,763. |
| 1B Jim McManus received a 1-year contract through automatic renewal worth a total of $14,763. |
| 1B Lee Thomas received a 1-year contract through automatic renewal worth a total of $14,763. |
| MR Carl Bouldin received a 1-year contract through automatic renewal worth a total of $14,763. |
| 2B Ken Hubbs received a 1-year contract through automatic renewal worth a total of $14,763. |
| C Don Leppert received a 1-year contract through automatic renewal worth a total of $14,763. |
| 3B Andy Carey becomes a free-agent. |
| C Joe Torre received a 1-year contract through automatic renewal worth a total of $14,763. |
| LF Frank Robinson becomes a free-agent. |
| CL Bob Kelly becomes a free-agent. |
| Thursday, November 9th, 1961 |
| MR Charlie Rabe received a 1-year contract through arbitration worth a total of $22,145. |
| SP Bob Gibson received a 1-year contract through arbitration worth a total of $220,000. |
| LF Chuck Coles received a 1-year contract through arbitration worth a total of $22,145. |
| C Dutch Dotterer received a 1-year contract through arbitration worth a total of $35,750. |
| CF Danny Morejon received a 1-year contract through arbitration worth a total of $22,145. |
| SP Jim O'Toole received a 1-year contract through arbitration worth a total of $42,000. |
| MR Al Jackson received a 1-year contract through arbitration worth a total of $22,145. |
| CF Vada Pinson received a 1-year contract through arbitration worth a total of $55,000. |
