| | | Sunday, March 11th, 1962 | | Signed LF Whitey Herzog to a 1-year contract extension worth a total of $28,325. |
| Tuesday, January 16th, 1962 | | Purchased the contract of CL Dave Giusti from Triple A Norfolk. |
| Saturday, December 2nd, 1961 | | Signed free agent CF Marty Keough to a 2-year contract worth a total of $100,800. | | Signed LF Matty Alou to a 3-year contract extension worth a total of $167,625. |
| Thursday, November 30th, 1961 | | Signed MR Wilbur Wood to a 2-year contract extension worth a total of $50,400. | | Drafted RF Tony Oliva in the 1961 first-year player draft (Round 1, Pick 4, 4th overall pick). | | Drafted MR Dave Giusti in the 1961 first-year player draft (Round 2, Pick 4, 28th overall pick). | | Drafted 3B Max Alvis in the 1961 first-year player draft (Round 3, Pick 5, 51st overall pick). | | Drafted RF Purnal Goldy in the 1961 first-year player draft (Round 4, Pick 6, 75th overall pick). | | Drafted MR Dave Gerard in the 1961 first-year player draft (Round 5, Pick 5, 99th overall pick). | | Drafted MR Jim Manning in the 1961 first-year player draft (Round 5, Pick 7, 101st overall pick). |
| Saturday, November 25th, 1961 | | Signed LF Ellis Burton to a 3-year contract extension worth a total of $120,200. | | Signed SP Von McDaniel to a 2-year contract extension worth a total of $44,290. | | Signed RF Dan Dobbek to a 2-year contract extension worth a total of $49,445. | | Signed SP Bill Stafford to a 3-year contract extension worth a total of $148,500. |
| Friday, November 24th, 1961 | | Signed free agent SP Bob Turley to a 1-year contract worth a total of $25,400. | | Signed SS Tom Tresh to a 3-year contract extension worth a total of $238,500. |
| Wednesday, November 22nd, 1961 | | Signed free agent SP Harvey Haddix to a 2-year contract worth a total of $48,600. |
| Tuesday, November 21st, 1961 | | Signed free agent LF Whitey Herzog to a 1-year contract worth a total of $27,500. | | Signed SP Ernie Broglio to a 2-year contract extension worth a total of $44,290. |
| Sunday, November 12th, 1961 | | SP Ernie Broglio received a 1-year contract through automatic renewal worth a total of $14,763. | | MR Chris Short received a 1-year contract through automatic renewal worth a total of $14,763. | | MR Bennie Daniels received a 1-year contract through automatic renewal worth a total of $14,763. | | LF Ellis Burton received a 1-year contract through automatic renewal worth a total of $14,763. | | MR Bobby Shantz becomes a free-agent. | | RF Dan Dobbek received a 1-year contract through automatic renewal worth a total of $14,763. | | CF Curt Flood becomes a free-agent. | | CF Duke Carmel received a 1-year contract through automatic renewal worth a total of $14,763. | | SS Tom Tresh received a 1-year contract through automatic renewal worth a total of $14,763. | | SP Wilbur Wood received a 1-year contract through automatic renewal worth a total of $14,763. | | C Earl Averill received a 1-year contract through automatic renewal worth a total of $20,000. | | SP Bill Stafford received a 1-year contract through automatic renewal worth a total of $14,763. | | SP Earl Wilson received a 1-year contract through automatic renewal worth a total of $14,763. | | LF Matty Alou received a 1-year contract through automatic renewal worth a total of $14,763. | | MR Joe McClain received a 1-year contract through automatic renewal worth a total of $14,763. | | 2B Jose Pagan received a 1-year contract through automatic renewal worth a total of $14,763. | | 3B Charley Smith received a 1-year contract through automatic renewal worth a total of $14,763. | | MR Hector Maestri received a 1-year contract through automatic renewal worth a total of $14,763. | | SP Von McDaniel received a 1-year contract through automatic renewal worth a total of $14,763. |
| Thursday, November 9th, 1961 | | MR Roger Craig received a 1-year contract through arbitration worth a total of $22,145. | | C Gene Green received a 1-year contract through arbitration worth a total of $22,145. | | 2B Eddie Kasko received a 1-year contract through arbitration worth a total of $22,145. | | C Hal Smith received a 1-year contract through arbitration worth a total of $22,145. |
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